Quarterly report pursuant to Section 13 or 15(d)

Note 10 - 2021 Registered Direct Offerings (Details Textual)

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Note 10 - 2021 Registered Direct Offerings (Details Textual) - USD ($)
 3 Months Ended 6 Months Ended
Feb. 22, 2021
Feb. 11, 2021
Mar. 31, 2023
Jun. 30, 2023
Stock Issued During Period, Shares, New Issues       215,625
Warrants and Rights Outstanding, Term       5 years
Series K Warrant [Member]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights   161,719   161,719
Warrants and Rights Outstanding, Term   5 years 6 months    
Placement Agent 2 Warrants [Member]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights   16,172   16,172
Class of Warrant or Right, Exercise Price of Warrants or Rights   $ 40.00    
Warrants and Rights, Percent of Stock Oustanding Callable   750.00%    
Series K and Placement Agent 2 Warrants [Member]        
Class of Warrant or Right, Exercised     0  
The 2021 Registered Direct Offering [Member]        
Stock Issued During Period, Shares, New Issues 215,625      
Shares Issued, Price Per Share   $ 32.00    
Class of Warrant or Right, Exercise Price of Warrants or Rights   $ 34.00    
Proceeds from Issuance or Sale of Equity   $ 6,900,000    
Payments of Stock Issuance Costs   700,000    
The 2021 Registered Direct Offering [Member] | Non-accountable Expense Fee [Member]        
Securities Purchase Agreement, Potential Fees   10,000    
The 2021 Registered Direct Offering [Member] | Fees and Expenses of Legal Counsel and Other Out-of-pocket Expenses [Member]        
Securities Purchase Agreement, Potential Fees   50,000    
The 2021 Registered Direct Offering [Member] | Clearing Expenses [Member]        
Securities Purchase Agreement, Potential Fees   $ 10,000    
The 2021 Registered Direct Offering [Member] | Participating Investors [Member]        
Securities Purchase Agreement, Cash Placement Fee   7.50%    
The 2021 Registered Direct Offering [Member] | Certain Investors With Pre-existing Relationships [Member]        
Securities Purchase Agreement, Cash Placement Fee   6.00%